Cedars-Sinai Research Associate III Prdm in Los Angeles, California

Job Posting: In a Research Associate III Per Diem, you will join a translational immunology lab whose focus is the role of the innate immune system in driving the autoimmune disease Lupus. Your role as a member of this team will to contribute to on-going projects which utilize molecular biology and immunological techniques to address on-going questions in the lab. Projects you might be involved include: Understanding what contributes to the development of lung disease or heart disease in Lupus patients; understanding how gene expression is regulated in Lupus immune cells. You will use both animal models and primary immune cells from Lupus patients to address these questions. JOB SUMMARY: Working under independently and in close collaboration with the PI, the Research Associate III performs complex laboratory tasks and procedures and has technical expertise in one or more areas relevant to research projects. The Research Associate II will participate in research activities involving all aspects of the research process, to include, but not limited to; investigation, technical, testing/validation of results, and report findings. The Associate will observe and comply with safety standards and procedures, assist in preparation of data for publication and/or presentation at scholarly meetings, and assist in general laboratory maintenance. This position will involve training of lab personnel in various techniques. DEPARTMENT AND/OR UNIT SPECIFIC – ESSENTIAL JOB RESPONSIBILITIES: Will have responsibility for characterizing and phenotyping Lupus neutrophils. This will include:

•Performing neutrophil isolation and prepping neutrophil samples;

•Overseeing sample analysis with genomics core – including bioinformatics;

•Carrying out chromatin immunoprecipitation and subsequent analysis;

•Carrying out immunoprecipitation and interfacing with mass spec core as needed.

•Assists clinical research coordinators with running trials and processing human specimen samples in the laboratory ESSENTIAL JOB DUTIES AND RESPONSIBILITIES: Performs a variety of complex experimental protocols and procedures and assist in the design of new complex or unusual protocols and techniques. Keeps accurate and detailed records of experiments and results, and assist in identifying and troubleshooting of unexpected results. Orders laboratory supplies and supports laboratory operations. Assists in the operation of specialized equipment, as required by the area of research. Assists in preparation of data for publication and/or presentation at scholarly meetings. Observes and complies with safety standards and procedures. Orients research laboratory assistants or lower level research associates and undergraduate student researchers on day-to-day lab operations and routine procedures. Leads and trains Research Lab Assistants, Research Fellow, lower level Research Associates, and other related support staff and may be requested by PI to take on specific supervisory activities. Orients new Research Fellows and/or Research Scientists to day-to-day lab operations and procedures.

Qualification Requirements/Preferences:

Education Certifications/Licensure Experience Physical Abilities Educational Requirements:

Bachelor of Science Degree, required. Master of Science Degree, preferred.

Experience:

Three to five (3-5) years of experience in area of research specialization. Has technical skills and expertise in an area of study including, but not limited to, Molecular/Cellular Biology, Neuroscience, engineering, or mass spectometry. Experience in cutting-edge histology/imaging techniques including quantitative bright-field and fluorescence microscopy, confocal microscopy, and electron microscopy is required. Strong computer skills (MS Word, MS Excel, MS Access, PowerPoint). Strong analytical and problem-solving skills; excellent organization skills and very detail-oriented; learns new tasks quickly; self-motivated; works well independently with minimal supervision; works well with others, and able to multitask. Strong interpersonal skills for interaction with peers, patients, physicians, and other customers of the medical center. Thorough technical and theoretical understanding of PI’s research objectives. Mastery of complex or unusual technical procedures and protocols. Ability to research, develop and implement new laboratory procedures and protocols. Knowledge of human resource and administration policies and procedures. Knowledge of budgetary requirements and policies

Physical Demands: (e.g., lifting, standing, walking)

Able to perform moderate lifting. Able to sit, stand and walk for prolonged periods of time. Able to read papers and online documents. Able to operate standard office equipment. Able to exercise physical ability and perspective acuity to satisfactorily perform essential job functions.