Cedars-Sinai Project Scientist - Department of Pathology - Tourtellotte Lab in Los Angeles, California
As a Project Scientist in the Department of Pathology, you will work independently and in cooperation with the Principal Investigator to make significant and creative contributions to an assigned research project. The research projects assigned are developed under the direction and in collaboration with the Principal Investigator, Warren Tourtellotte, MD, PhD, Professor and Vice-Chair of Pathology and Laboratory Medicine and Professor of Neurology, Neurosurgery and Biomedical Sciences. You will be expected to have substantial scientific independence, organization, creativity and motivation. A significant track-record of scholarly productivity and strong evidence of successful independent experimental design and execution is expected and essential. This role will include studying the role of microglia in Alzheimer’s Disease pathogenesis and evaluating molecules that can modulate microglial function and neurotoxic beta-amyloid processing and homeostasis in the brain. Depending on the candidate’s expertise, projects related to development and degeneration of the peripheral nervous system are available. The candidate will be expected to independently design and conduct experiments, collect and analyze data, troubleshoot experimental protocols, consolidate data for publication and grant applications, present research at national and international meetings, and prepare manuscripts for publication. Teaching and supervising other research staff, students, and residents may be required.
- PhD (preferably with expertise in neuroscience, neurobiology, molecular biology or a closely related field) is required
Must have a minimum of 2 years of experience as a scientifically productive post-doctoral fellow.
Must have experience with translational research using animal models to study mechanisms of gene function and disease pathogenesis.
Experience in molecular biology, cell culture, immunocytochemistry, Western blotting, PCR, quantitative real-time PCR and histology/imaging techniques including quantitative bright-field and fluorescence microscopy and confocal microscopy is required.
Experience with proteomics analysis of isolated protein complexes will be beneficial for some of the planned protein-protein interaction experiments.
Cedars-Sinai is an EEO employer. Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law.