Cedars-Sinai Postdoctoral Scientist (Molecular Mechanism of Cancer) in Los Angeles, California

This Postdoctoral Scientist opportunity is for an NIH-NCI supported laboratory of Dr. Jlenia Guarnerio in the Department of Radiation Oncology and Department of Biomedical Sciences at Cedars-Sinai Medical Center in Los Angeles, CA. The Guarnerio lab will focus on understanding the molecular mechanisms of cancer, with a particular emphasis on leukemia and sarcoma. We are interested in studying both cell-autonomous mechanisms responsible for cancer progression (e.g cancer expression profile), as well as non-cell-autonomous ones (e.g. derived from the tumor microenvironment). To dissect cancer-specific vulnerabilities, we will combine techniques of biochemistry, molecular biology, and Crispr/Cas9 technologies, together with next generation sequencing, multicolor flow cytometry, and the use of innovative mouse models. Our final goal is to identify novel therapeutic interventions for cancer, and new strategies of precision medicine.

For this Postdoctoral Scientist position, the candidate would be expected to work independently on research projects designed in conjunction with Dr. Guarnerio. The Postdoctoral Scientist will assist in designing and conducting experiments, collection and analysis of data, preparation of data for publication and grant submission, presenting at both local and national meetings and applying for fellowships and grants. Teaching of other research staff, students, residents and fellows may be required.

Postdoctoral appointment will be for 1-3 years with the possibility for extension based on productivity and research.

Educational Requirements:

•PhD or MD/PhD degree in a Biology or Biomedical discipline


The ideal candidate will have:

•Sound technical skills and general experience in mouse modeling, RNA biology, cancer biology and/or molecular biology

•Publication track record

•Excellent oral and written communication skills

•PhD or MD-PhD degree obtained no more than two years ago

•Ability to perform and prioritize multiple simultaneous tasks.

•Candidate should be industrious, highly collaborative, and enthused by a vibrant team environment.

Candidates with experience in immunology, cancer biology of solid tumors or leukemia, basic bioinformatics and mouse modeling are preferred. Experience with molecular biology, cell culture and willingness to work with murine models is required. Familiarity with flow cytometry, advanced sequencing techniques and bioinformatics is preferred but not required.