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Cedars-Sinai Postdoctoral Scientist - Gayther Lab - Center for Bioinformatics & Functional Genomics in Los Angeles, California

The Center for Bioinformatics and Functional Genomics at Cedars-Sinai Medical Center is seeking a Postdoctoral Scientist to join the lab of Dr. Simon Gayther!

The Center brings together teams specializing in cell biology, computational biology, functional analysis of the genome coupled with next generation sequencing and genome editing to provide a complete pipeline for identifying the functional consequences of identified cancer risk loci.

Dr. Gayther’s research program is largely focused on understanding the underlying causes of ovarian, breast, and prostate cancer development. The lab is working to define the heritable component and the functional role of both common and rare risk variants and their target susceptibility genes in the early stage disease pathogenesis. For more information, please visit https://www.cedars-sinai.org/research/labs/gayther.html .

Working independently but in close cooperation and in consultation with the Principal Investigator and other Research Scientists, the Postdoc will perform routine and complex laboratory procedures throughout training period, and may develop, adapt, and implement new research techniques and protocols. This role analyzes and interprets data, may assist in preparation of grant proposals, and participates in publications and presentations as author or co-author. This position is not responsible for generating grant funds.

Additional Duties and Responsibilities:

  • Design, implement and execute conducting a CRISPR Cas9 screen

  • Manage the day to day running of specific experiments

  • Abide by Animal Licenses, IRB protocols, and SOP relating to projects in the laboratory

  • Supervise graduate student/RA on relevant projects

  • Undertake research projects that are part of the research program under the direction of principal Investigator or designated investigators

  • Present at national/international conferences, internal seminars

  • Assist in day to day activities in running the laboratory


Educational Requirements:

  • Doctorate (MD, PhD, VMD, or DDS) in area directly related to field of research specialization


  • Experience in genetics, genomics and genome editing

  • Experience in generally molecular biology techniques such as PCR, cloning, plasmid manipulation, siRNA/CRISPR knockdown

  • Experience in cell culture, cell biology assays and modeling of disease

  • Experience in high throughput screening approaches

  • Experience in generating next generation sequencing data

Cedars-Sinai is an EEO employer. Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law.