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Cedars-Sinai Postdoctoral Scientist - Department of Medicine - Lung Institute - Chen Lab in Los Angeles, California

The Chen Laboratory is unraveling basic mechanisms of lung injury and repair. Our focus is on how lung epithelial cells interact with other cellular compartments and with the extracellular matrix to regulate inflammatory cell recruitment and lung fibrosis in various cell-based and animal models.

Job summary:

Applications are being solicited for federally-funded basic and translational research fellowships in respiratory biology and diseases. The work will be conducted in the laboratory of Dr. Peter Chen, who has a research program in lung injury and repair. His laboratory is part of the Lung Institute is comprised of several top researchers that have vibrant research programs in lung injury, fibrosis, infection, regeneration, and immunology (https://www.cedars-sinai.edu/Research/Research-Areas/Pulmonary/index.aspx). The Chen lab employs a variety of cell-based assays, animal models, and human tissues merged with novel technologies such as single cell RNA sequencing to conduct high impact research in respiratory diseases. Representative publications of ongoing areas of research in the Chen lab include:

JCI Insight. 2019 Aug 8;5(17):e

  1. doi: 10.1172/jci.insight.

  2. Am J Pathol. 2018 Apr;188(4):1094-

  3. doi: 10.1016/j.ajpath.2017.12.

  4. JCI Insight. 2016 Dec 8;1(20):e

  5. doi: 10.1172/jci.insight.

  6. Am J Respir Crit Care Med. 2016 Aug 1;194(3):333-

  7. doi: 10.1164/rccm.201509-1878OC.

Am J Respir Cell Mol Biol. 2016 Aug;55(2):243-

  1. doi: 10.1165/rcmb.2015-0193OC.

J Biol Chem. 2012 Oct 12;287(42):34927-

  1. doi: 10.1074/jbc.M112.

  2. J Cell Sci. 2012 Nov 1;125(Pt 21):5188-

  3. doi: 10.1242/jcs.

  4. As a Postdoctoral Fellow, you will work independently but in close cooperation and in consultation with the Principal Investigator and other Research Scientist. You will perform routine and complex laboratory procedures throughout training period, develop, adapt, and implement new research techniques and protocols, and analyze and interpret data. This position is not dependent on generating independent funding but may assist in preparation of grant proposals. Our Postdoctoral Fellows are expected to develop a project and generate results that lead to publications and presentations as author or co-author. Career development will be provided to support the growth of Postdoctoral Fellows into various careers in academia or industry.   

Will facilitate the research of the laboratory by:

  • Orienting new laboratory members to the policies and regulations for their research.

  • Making sure the laboratory is up to date in all policies and regulations required by the various oversight committees.

  • Monitors and ensures compliance with safety standards and procedures.

  • Independently creating and updating protocols for all research in the laboratory (e.g., IACUC).

  • Understand the basic premise of all the laboratory projects and helping laboratory members carry out their research as needed.

Facilitate publications and grant applications by:

  • Generating new data for the research project.

  • Analyzes data and prepares scientific findings for publication as author or co-author.

  • Work independently on a project and push it forward into novel areas.

  • Help other laboratory members move their project in novel directions.

  • Compile and organize the data generated by members of the laboratory and create appropriate figures with statistical analysis.

  • Overseeing all work in the laboratory to ensure it is carried out with the highest scientific rigor.

Other duties include:

  • Providing miscellaneous clinical/research support (ad hoc data analysis, hypothesis development, programming, troubleshooting, etc.).

  • Organizing clinical/research trials in conjunction with the Principal Investigator and sponsor and/or funding source.

  • Making independent presentations.

  • Providing system administration and maintenance for the local workstation network.

  • Training Research Lab Assistants, Research Fellow, lower level Research Associates, and other related support staff and may be requested by PI to take on specific supervisory activities.

Education required:

  • Doctorate (MD, PhD, VMD, or DDS) in area directly related to field of research specialization is required

Experience required:

  • Works independently on research projects designed by a mentor (typically the PI) within area of specialization.

  • Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment.

  • Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis and operation and maintenance of specialized equipment.

  • Knowledge of safety standards and maintenance of specialized equipment.

Cedars-Sinai is an EEO employer. Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law.